Official UK procurement notice
Tumour Infiltrating Lymphocyte (TIL) Therapy hubs for Melanoma (Adults)
Authority: NHS England (Central government)
What is being bought7 lots · detail below
Published requirement descriptionNHS Arden and Greater East Midlands Commissioning Support Unit (AGCSU), on behalf of NHS England -Specialised Commissioning (referred to as the Authority), is inviting suitably qualified and experienced providers to respond to this Competitive Process for the provision of Tumour Infiltrating Lymphocyte (TIL) Therapy hubs for Melanoma (Adults).<br/><br/>As a result of this procurement exercise an agreement will be established with the successful bidder(s) for a period of three (3) years with the Commissioners having the option to extend for up to an additional two (2) year(s) (maximum contract duration 5 years).<br/><br/>The deadline for submissions is 12.00pm (noon) on Tuesday 24th June 2025.
CPV: Health services
Lots and requirements (7)Procurement structure
7 lots · all with a published value (£69,910,000 together) · a supplier may bid for at most 1 and win at most 1 of themLot #1London (2 Sites) LondonPublished value£17,470,000
The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, with two (2) sites in London. <br/><br/>Providers may only bid for one Lot. Bids submitted for multiple lots will not be considered. <br/><br/>Bidders are to note that Providers must be located in and deliver services from the defined geographical area(s) that they are interested in providing services to. <br/><br/>Link to NHS England Regions:<br/>NHS England » Regional teams (www.england.nhs.uk/about/regional-area-… ↗).<br/><br/>As a result of this procurement exercise an agreement will be established with the successful bidder(s) for a period of three (3) years with the Commissioners having the option to extend for up to an additional two (2) year(s) (maximum contract duration 5 years).<br/><br/>The deadline for submissions is 12.00pm (noon) on Tuesday 24th June 2025.
Lot #2East of England (1 Site) East of EnglandPublished value£8,740,000
The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, with one (1) site in the East of England. <br/><br/>Providers may only bid for one Lot. Bids submitted for multiple lots will not be considered. <br/><br/>Bidders are to note that Providers must be located in and deliver services from the defined geographical area(s) that they are interested in providing services to. <br/><br/>Link to NHS England Regions:<br/>NHS England » Regional teams (www.england.nhs.uk/about/regional-area-… ↗).<br/><br/>As a result of this procurement exercise an agreement will be established with the successful bidder(s) for a period of three (3) years with the Commissioners having the option to extend for up to an additional two (2) year(s) (maximum contract duration 5 years).<br/><br/>The deadline for submissions is 12.00pm (noon) on Tuesday 24th June 2025.
Lot #3South East (1 Site) South EastPublished value£8,740,000
The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, with one (1) site in the South East. <br/><br/>Providers may only bid for one Lot. Bids submitted for multiple lots will not be considered. <br/><br/>Bidders are to note that Providers must be located in and deliver services from the defined geographical area(s) that they are interested in providing services to. <br/><br/>Link to NHS England Regions:<br/>NHS England » Regional teams (www.england.nhs.uk/about/regional-area-… ↗).<br/><br/>As a result of this procurement exercise an agreement will be established with the successful bidder(s) for a period of three (3) years with the Commissioners having the option to extend for up to an additional two (2) year(s) (maximum contract duration 5 years).<br/><br/>The deadline for submissions is 12.00pm (noon) on Tuesday 24th June 2025.
Lot #4South West (1 Site) South WestPublished value£8,740,000
The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, with one (1) site in the South West. <br/><br/>Providers may only bid for one Lot. Bids submitted for multiple lots will not be considered. <br/><br/>Bidders are to note that Providers must be located in and deliver services from the defined geographical area(s) that they are interested in providing services to. <br/><br/>Link to NHS England Regions:<br/>NHS England » Regional teams (www.england.nhs.uk/about/regional-area-… ↗).<br/><br/>As a result of this procurement exercise an agreement will be established with the successful bidder(s) for a period of three (3) years with the Commissioners having the option to extend for up to an additional two (2) year(s) (maximum contract duration 5 years).<br/><br/>The deadline for submissions is 12.00pm (noon) on Tuesday 24th June 2025.
Lot #5Midlands (1 Site) East Midlands, West MidlandsPublished value£8,740,000
The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, with one (1) site in the Midlands. <br/><br/>Providers may only bid for one Lot. Bids submitted for multiple lots will not be considered. <br/><br/>Bidders are to note that Providers must be located in and deliver services from the defined geographical area(s) that they are interested in providing services to. <br/><br/>Link to NHS England Regions:<br/>NHS England » Regional teams (www.england.nhs.uk/about/regional-area-… ↗).<br/><br/>As a result of this procurement exercise an agreement will be established with the successful bidder(s) for a period of three (3) years with the Commissioners having the option to extend for up to an additional two (2) year(s) (maximum contract duration 5 years).<br/><br/>The deadline for submissions is 12.00pm (noon) on Tuesday 24th June 2025.
Lot #6North East and Yorkshire (1 Site) North East, Yorkshire & HumberPublished value£8,740,000
The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, with one (1) site in the North East and Yorkshire.<br/><br/>Providers may only bid for one Lot. Bids submitted for multiple lots will not be considered. <br/><br/>Bidders are to note that Providers must be located in and deliver services from the defined geographical area(s) that they are interested in providing services to. <br/><br/>Link to NHS England Regions:<br/>NHS England » Regional teams (www.england.nhs.uk/about/regional-area-… ↗).<br/><br/>As a result of this procurement exercise an agreement will be established with the successful bidder(s) for a period of three (3) years with the Commissioners having the option to extend for up to an additional two (2) year(s) (maximum contract duration 5 years).<br/><br/>The deadline for submissions is 12.00pm (noon) on Tuesday 24th June 2025.
Lot #7North West (1 Site) North WestPublished value£8,740,000
The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, with one (1) site in the North West. <br/><br/>Providers may only bid for one Lot. Bids submitted for multiple lots will not be considered. <br/><br/>Bidders are to note that Providers must be located in and deliver services from the defined geographical area(s) that they are interested in providing services to. <br/><br/>Link to NHS England Regions:<br/>NHS England » Regional teams (www.england.nhs.uk/about/regional-area-… ↗).<br/><br/>As a result of this procurement exercise an agreement will be established with the successful bidder(s) for a period of three (3) years with the Commissioners having the option to extend for up to an additional two (2) year(s) (maximum contract duration 5 years).<br/><br/>The deadline for submissions is 12.00pm (noon) on Tuesday 24th June 2025.
Procedure terms & legal framework
From the official record · publisher note attached- Procedure method
- Open procedure
- Legal basis
- CELEX · 32014L0024 Public Contracts Regulations 2015 (Directive 2014/24/EU)
- Procurement category
- Services
- Notice status
- Closed
- Procurement threshold
- Unspecified in notice
- Regulatory regime
- Standard
- Commercial structure
- Stand-alone contract (no framework)
- Competition type
- Competitive procedure
- GPA / WTO covered
- Yes (GPA)
- Recurring procurement
- Yes
- First published
- 16 May 2025, 11:57 BST
- Last source update
- 8 Jul 2025, 13:43 BST
- Award evaluation window
- 24 Jun 2025 – …
- FTS notice number
2025/S 000-038239- Classification (CPV)
- Delivery area
- Official registry OCID
ocds-h6vhtk-0515a8Find a Tender
Publisher note: The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, across seven (7) geographical lots as outlined below, to serve the population of England. <br/><br/>Lot 1: London (2 sites)<br/>Lot 2: East of England (1 site)<br/>Lot 3: South East (1 site)<br/>Lot 4: South West (1 site)<br/>Lot 5: Midlands (1 site)<br/>Lot 6: North East and Yorkshire (1 site)<br/>Lot 7: North West (1 site)<br/><br/>Bidders are to note that Providers must be located in and deliver services from the defined geographical area(s) that they are interested in providing services to. <br/><br/>Link to NHS England Regions:<br/>NHS England » Regional teams (https://www.england.nhs.uk/about/regional-area-teams/). <br/><br/>Lifileucel is a first in class autologous tumour infiltrating lymphocyte (TIL) cell therapy. This infusion is followed by a short course of interleukin-2 (IL-2). IL-2 is a potent drug and has the potential to cause significant side effects. As such, it is recommended that patients receive treatment at a Trust with immediate access to Intensive Therapy Unit (ITU). <br/><br/>Lifileucel is being assessed via NICE’s technology appraisal programme for previously treated unresectable or metastatic melanoma in adults, with an expected final guidance publication date of 10th December 2025. <br/><br/>Link for the current NICE paperwork:<br/>https://www.nice.org.uk/guidance/indevelopment/gid-ta10752<br/><br/>Providers are required to be an established site for the delivery of specialist skin cancer care that complies with the requirements as set out in the following specification: https://www.england.nhs.uk/wp-content/uploads/2018/08/Cancer-skin-adult.pdf<br/><br/>Providers must also;<br/>• Have access to surgical expertise which enables them to perform tumour resections to obtain enough sample tissue for final product to be made. <br/>• hold the appropriate Human Tissue Authority licences, which includes having the licence to cover the procurement, donor testing and exporting of the resected tissue.<br/>• Have expertise in delivering and managing cellular therapies <br/>• Have experience of managing the adverse effects of interleukin 2 inhibitors. Examples of these adverse events would be those similar to cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome.<br/>• Hold a Joint Accreditation Committee of ISCT and EBMT of the European Society for Blood and Marrow Transplantation (JACIE) Immune Effector Cells (IEC) accreditation or be working towards such accreditation. <br/>• Be a Heamotopoietic Stem Cell Transplantation centre <br/><br/>Providers must be able to meet the requirements set out in this Competitive Process and deliver the contract in accordance with its terms.<br/><br/>To express interest and participate in the Competitive Process, please register and apply via Atamis esourcing portal https://health-family.force.com/s/Welcome<br/><br/>Should Tenderers have any queries, or problems using the portal, they should contact the Helpdesk at: <br/>Phone: 0800 9956035<br/>E-mail: [email protected]<br/><br/>The closing date for completed Competitive Process responses is 12:00pm (noon), on Tuesday 24th June 2025.<br/><br/>Atamis Project reference C41701<br/><br/>The contract duration is for three (3) years with the Commissioners having the option to extend for up to an additional two (2) year(s) (maximum contract duration five (5) years).<br/><br/>This is a Provider Selection Regime (PSR) Contract Notice. The awarding of this contract is subject to the Health Care Services (Provider Selection Regime) Regulations 2023. For the avoidance of doubt, the provisions of the Public Contracts Regulations 2015 do not apply to this award.<br/><br/>The decision maker of the award will be: NHS England
How it was run
Official noticeTender documents are also served through a separate tool: https://health-family.force.com/s/Welcome ↗
- Submission deadline
- 1 Jul 2025, 12:00 BST
- Submission channel
- {"electronicSubmission","written"}
- Accepted languages
- en
- Bids opened
- 24 Jun 2025, 12:00 BST
Timeline
24 Jun 2025 → 21 Dec 2025 · 5 dates- Bids opened24 Jun 2025, 12:00 BST
- Submission deadline1 Jul 2025, 12:00 BST
- Notice published8 Jul 2025, 13:43 BST
- Contract starts363 days ago31 Oct 2025
- Bids must remain valid until311 days ago21 Dec 2025, 23:59 GMT
Notice history
1 event · 4 releases on Find a Tender- Deadline moved to 1 Jul 2025, 12:00 BST13 Jun 2025, 10:25 BST+7 days · was 24 Jun 2025, 12:00 BST
Published amendments (3 · 1 deadline change)
| When | What | Before | After | Shift |
|---|---|---|---|---|
| — | TextVI.3.0.1 | The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, across seven (7) geographical lots as outlined below, to serve the population of England. Lot 1: London (2 sites)Lot 2: East of England (1 site)Lot 3: South East (1 site)Lo… | The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, across seven (7) geographical lots as outlined below, to serve the population of England.Lot 1: London (2 sites)Lot 2: East of England (1 site)Lot 3: South East (1 site)Lot… | |
| — | DeadlineIV.2.2.1 | 24 Jun 2025 | 1 Jul 2025 | +7 d |
| — | Bid openingIV.2.7.1 | 24 Jun 2025 | 1 Jul 2025 | +7 d |
| — | TextII.1.4.1 | NHS Arden and Greater East Midlands Commissioning Support Unit (AGCSU), on behalf of NHS England -Specialised Commissioning (referred to as the Authority), is inviting suitably qualified and experienced providers to respond to this Competitive Process for the provision of Tumour Infiltrating Lymphocyte (TIL) Therapy hubs for Melanoma (Adults).As a result of this procurement exercise an agreement w… | NHS Arden and Greater East Midlands Commissioning Support Unit (AGCSU), on behalf of NHS England -Specialised Commissioning (referred to as the Authority), is inviting suitably qualified and experienced providers to respond to this Competitive Process for the provision of Tumour Infiltrating Lymphocyte (TIL) Therapy hubs for Melanoma (Adults).As a result of this procurement exercise an agreement w… | |
| — | TextVI.3.0.1 | The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, across seven (7) geographical lots as outlined below, to serve the population of England. Lot 1: London (2 sites)Lot 2: East of England (1 site)Lot 3: South East (1 site)Lo… | The key objectives of the Procurement are to commission eight (8) Tumour Infiltrating Lymphocyte (TIL) Therapy Hubs for adult patients, for the provision of Lifileucel for previously treated unresectable or metastatic melanoma, across seven (7) geographical lots as outlined below, to serve the population of England. Lot 1: London (2 sites)Lot 2: East of England (1 site)Lot 3: South East (1 site)Lo… | |
| — | TextII.1.4.1 | NHS Arden and Greater East Midlands Commissioning Support Unit (AGCSU), on behalf of NHS England -Specialised Commissioning (referred to as the Authority), is inviting suitably qualified and experienced providers to respond to this Competitive Process for the provision of Tumour Infiltrating Lymphocyte (TIL) Therapy hubs for Melanoma (Adults).As a result of this procurement exercise an agreement w… | NHS England has taken the decision to abandon this competitive provider selection process (effective from 30th June 2025) for lifileucel, a cellular therapy for previously treated unresectable or metastatic melanoma (NICE ID 3863). NHS England remains committed to commissioning this service, as this tumour infiltrating lymphocyte cell therapy progresses through the NICE TA process, in line with th… |
3 amendments published without a description.
Routine re-releases (4)
- 2025-05: 1 release · 16 May 2025
Contracting authority & participating public bodies
Dispute resolution & review bodies
Official documents & specifications
Official links; attachments are not copiedNo document links were published on the notice.