Official UK procurement notice
Purchase of High Content Screening System
Authority: Scottish National Blood Transfusion Service
What is being bought
Published requirement descriptionDelivery of an Operetta CLS high-content screening system
CPV: Wide field microscopes
The lotProcurement structure
single lot · no lot value publishedLot #1Supply, installation and training of High Content Screening System Operetta CLS…
Supply, installation and training of High Content Screening System Operetta CLS equipment for the detailed analysis of a variety of cell types (including rare cells such as stem cells and antigen-specific T cells) and for more specialist applications including: imaging of primary cells, live cells and cells cultured in 3D systems, tumorigenesis analysis including colony detection, phagocytosis assays, size and shape analysis, quantification of cells/colonies and fluorescence; by TCAT (Tissues, Cells and Advanced Therapeutics), Scottish National Blood Transfusion Service (SNBTS).
The following specific aspects of operetta CLS are strictly necessary for our research and are not provided by any other provider:
— With 8 high-performance LEDs, the Operetta CLS offers an unsurpassed variety of excitation wavelengths for the entire range between ultraviolet and near-infrared. This flexibility is of immense importance for QC development of a wide variety of assays
— The Operetta CLS has a user-accessible 8-position emission filter wheel, which can be equipped with barcode filters for error-free operation, and for optimal coincidence between excitation and emission source.
.— The Operetta CLS can be equipped with 3 automated water immersion lenses with high numerical aperture of various magnifications (20x, 40x, 63x). This shortens the measurement time and improves the resolution in the z-direction; overall, this increases throughput in the analysis of three-dimensional structures. This is necessary for the exact analysis of the many different samples that are measured in our central department (tissue sections, tumor organoids, cell culture experiments, etc.). This technology is patented: EP1386189 B1, US7304793 B2 and EP1646902 B1, US7961384 B2.
— The system automatically corrects displacements resulting from the 5x to the 40x or 63x lens by means of a fluorescent reference sample (QuasiperiodicGrid) firmly installed in the table. This ensures that the desired cells, cell complexes, or cell structures can be found again and again at the
right level. Perkin Elmer also has a patent (US9582864). The ability to pre-scan and return to the same spot reduces the amount of time that cells are expose3d to incident illumination and therefore limits damage to the cells, this allows repeat analysis and temporal tracking.
— That the equipment software offers advanced morphological characteristics that allow the quantification of various aspects of the shape and structure of objects, for example: elongation, symmetry, smoothness of the edge and spatial distribution of the intensity of the texture characteristics,
— The system offers a method for machine learning (PhenoLOGIC) during analysis. This allows the software to identify different cell populations or regions and then automatically set the best parameters for optimal image segmentation and cell classification (patents to PhenoLOGIC:WO2013038224).
Procedure terms & legal framework
From the official record · publisher note attached- Procedure method
- Negotiated without publication of a contract notice
- Legal basis
- CELEX · 32014L0024 Public Contracts Regulations 2015 (Directive 2014/24/EU)
- Procurement category
- Goods
- Notice status
- Awarded
- Procurement threshold
- Unspecified in notice
- Regulatory regime
- Standard
- Commercial structure
- Stand-alone contract (no framework)
- Competition type
- Competitive procedure
- GPA / WTO covered
- Yes (GPA)
- Recurring procurement
- Unspecified in notice
- First published
- 27 Jan 2021, 09:56 GMT
- Last source update
- 27 Jan 2021, 09:56 GMT
- FTS notice number
2021/S 000-001601- Classification (CPV)
- Delivery area
- Official registry OCID
ocds-h6vhtk-028d97Find a Tender
- Why no open competition
The works, supplies or services can be provided only by a particular economic operator due to absence of competition for technical reasons
- Published justification
The following specific and unique selling points of operetta CLS are strictly necessary for our research and are not provided by any other provider:
— With 8 high-performance LEDs, the Operetta CLS offers an unsurpassed variety of excitation wavelengths for the entire range between ultraviolet and near-infrared. This flexibility is of immense importance for QC development of a wide variety of assays
— The Operetta CLS has a user-accessible 8-position emission filter wheel, which can be equipped with barcode filters for error-free operation, and for optimal coincidence between excitation and emission source.
.— The Operetta CLS can be equipped with 3 automated water immersion lenses with high numerical aperture of various magnifications (20x, 40x, 63x). This shortens the measurement time and improves the resolution in the z-direction; overall, this increases throughput in the analysis of three-dimensional structures. This is necessary for the exact analysis of the many different samples that are measured in our central department (tissue sections, tumor organoids, cell culture experiments, etc.). This technology is patented: EP1386189 B1, US7304793 B2 and EP1646902 B1, US7961384 B2.
— The system automatically corrects displacements resulting from the 5x to the 40x or 63x lens by means of a fluorescent reference sample (QuasiperiodicGrid) firmly installed in the table. This ensures that the desired cells, cell complexes, or cell structures can be found again and again at the
right level. Perkin Elmer also has a patent (US9582864). The ability to pre-scan and return to the same spot reduces the amount of time that cells are expose3d to incident illumination and therefore limits damage to the cells, this allows repeat analysis and temporal tracking.
— That the equipment software offers advanced morphological characteristics that allow the quantification of various aspects of the shape and structure of objects, for example: elongation, symmetry, smoothness of the edge and spatial distribution of the intensity of the texture characteristics,
— The system offers a method for machine learning (PhenoLOGIC) during analysis. This allows the software to identify different cell populations or regions and then automatically set the best parameters for optimal image segmentation and cell classification (patents to PhenoLOGIC:WO2013038224).
Publisher note: NOTE: To register your interest in this notice and obtain any additional information please visit the Public Contracts Scotland Web Site at https://www.publiccontractsscotland.gov.uk/Search/Search_Switch.aspx?ID=641947. (SC Ref:641947)
Commercial outcome & contract awards
Published awards, contracts and bid statistics, not a forecast| Awarded to | Value | Date | Status |
|---|---|---|---|
| Perkin Elmer | — | — | Awarded |
Contracts
Contract 001601-2021-1 · Perkin Elmer
- Signed
- 22 Jan 2021
- Value
- —
- Status
- active
Bid statistics published by the authority
| Lot | Bids | SME | VCSE | Valid bid range |
|---|---|---|---|---|
| Supply, installation and training of High Content Screening System Operetta CLS… | — | — | — | £200,000 – £300,000 |
| Whole notice | — | — | — | £200,000 – £300,000 |
Contracting authority & participating public bodies
Dispute resolution & review bodies
- Edinburgh Sheriff CourtReview body
Bidders & participating suppliers
1 commercial party on the notice- Perkin ElmerAwarded supplier
Official documents & specifications
Official links; attachments are not copiedNo document links were published on the notice.