Patchliner automated ePhys patch-clamping system

CPV: Imaging equipment for medical, dental and veterinary use

Procedure method

Award procedure without prior publication of a call for competition

Legal basis

CELEX · 32014L0024 Public Contracts Regulations 2015 (Directive 2014/24/EU)

Procurement category

Goods

Notice status

Awarded without competition

Procurement threshold

Unspecified in notice

Regulatory regime

Standard

Commercial structure

Stand-alone contract (no framework)

Competition type

Direct award (no call for competition)

GPA / WTO covered

Yes (GPA)

Recurring procurement

Unspecified in notice

First published

26 Jan 2021, 10:16 GMT

Last source update

16 May 2022, 09:20 BST

Authority reference

CU.529.SF

FTS notice number

2022/S 000-012569

Classification (CPV)

Imaging equipment for medical, dental and veterinary use

Delivery area

Wales (UKL22)

Official registry OCID

ocds-h6vhtk-028d41 Find a Tender

Why no open competition

The works, supplies or services can be provided only by a particular economic operator due to absence of competition for technical reasons

Published justification

The Patchliner is a fully automated planar patch-clamping system with unparalleled versatility, compared to rival automated systems, and ease-of-use compared to conventional patch-clamping, which requires several months specialist training. This ease-of-use is the key attribute, as high quality electrophysiology data can be generated after just one training session, making the equipment realistically multi-user and allowing PhD or undergraduate students to perform otherwise complex ion channel electrophysiological recordings. The equipment will allow basic research into ion channel function, such as ion permeability, voltage dependency, and the effects of ligands and modulators on these, and ion channel directed drug discovery, by researchers who are not expert electrophysiologists. Planar patch-clamping systems utilise borosilicate glass chips with a micron size aperture, embedded in a microfluidic chamber, to take the place of pipettes in a conventional patch-clamping set up. Negative pressure attracts cells to the aperture, where a reliable seal is formed automatically with the cell, allowing recording of ion flux. We will use this equipment for 1) ion channel targeted drug discovery, 2) characterisation of differentiated stem cell models (e.g. neurons, cardiomyocytes), 3) phenotypic characterisation of ion channels, 4) characterisation of pore-forming toxin ion permeability, 5) ion flux in plant cells and 6) the impact of biomaterials and artificial amino acids on ion channel function.

Publisher note: (WA Ref:121324)

• Nanion Technologies GmbHAwarded supplier Ganghoferstr. 70A, Muenchen, DE212, 80339Contact phoneShow contact details

No document links were published on the notice.