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Official procurement procedure
Equipment including single use bioreactors, biosealers, biowelders, benchtop controllers for stirred and rocking motion systems plus Single Use Centrifugal systems for the use in the manufacture of gene therapy drugs/treatment for research and development, education/teaching and training
Biomedical equipment
Installation services of laboratory equipment
Published value
Not published
Submission deadline Not published
Lots published1
Procurement Executive Summary
AI & Search Synopsis
Generated from official OCDS record
Tenderline Synopsis: UNIVERSITY OF SHEFFIELD: "Equipment including single use bioreactors, biosealers, biowelders, benchtop controllers for stirred and rocking motion systems plus Single Use Centrifugal systems for the use in the manufacture of gene therapy drugs/treatment for research and development, education/teaching and training". Published status: complete. Published value: Value not published. 1 published lot. Submission deadline not published. See the official notice for participation instructions.
| Contracting Authority | UNIVERSITY OF SHEFFIELD | Scope & Categories | Not published | Submission Window | complete No deadline published |
|---|---|---|---|---|---|
| Submission Gateway | Direct notice route | Legal Basis & Regime | Standard procurement | Estimated Value (exc. VAT) | Not published |
Bidder Intelligence · Authority Profile: UNIVERSITY OF SHEFFIELD
Market Analytics
Derived from OCDS awards & bid statistics
Published history for UNIVERSITY OF SHEFFIELD. These figures describe retained records, not a forecast of bids or a measure of buyer bias.
Average Price Reduction
Not availableInsufficient comparable data
Competition Density
1Bids / Report
Supplier ConcentrationNo estimate
Insufficient attributable awardsNo concentration estimate availablePayment Terms
Check noticePublished terms
Coverage: 3 active published awards; 3 bid reports (which may be per lot). Supplier values exclude multi-supplier awards, frameworks and DPS, and use GBP only. They are published award values, not payments. Price reduction compares single-lot, single-award, single-supplier GBP procedures with explicitly non-framework/non-DPS status; increases remain in the average. Unpublished data stays unknown. Awarded suppliers are winners, not all bidders.
Procedure terms
Contracting AuthorityUNIVERSITY OF SHEFFIELD | Procedure methodNot published | Procurement categoryNot published |
Statuscomplete | Framework / DPSNot published | CompetitionNot published |
Above thresholdNot published | Legal basisNot published | Tender period startsNot published |
Clarification deadlineNot published | Electronic submissionNot published | Submission languagesNot published |
Published27 Jul 2022, 11:15 BST | Last source update27 Jul 2022, 11:15 BST | Recurring procurementNot published |
ClassificationBiomedical equipment, Installation services of laboratory equipment | ||
Delivery area | ||
OCIDocds-h6vhtk-03027f | ||
What is being bought
The University of Sheffield (UoS) is establishing a new 'Gene Therapy Innovation Manufacturing Centre' (GTIMC) to advance scientific discoveries into life-changing treatments for patients with life threatening diseases. The Sheffield GTIMC will be one of three cutting edge hubs in the UK dedicated to advancing the clinical development of new genetic treatments. This facility is due to open in the Summer of 2022 and further details can be found at the following link:-
https://www.sheffield.ac.uk/news/new-gene-therapy-innovation-centre-advance-scientific-discoveries-life-changing-treatments
The UoS requires various bioreactors and complimentary/integrated equipment (sealer, welder etc), in order to undertake this co-ordinated work in parallel to 2 other UK sites (NHS Blood and Transplant (Bristol) and Kings College London working on identical methods and processes. To ensure the consistency of the science and comparability of the results, the same equipment needs to be purchased as the other two facilities.
What changed
From the official release history
- Official notice release published
27 Jul 2022, 11:15 BST - Buyer information updated
27 Jul 2022, 11:15 BST - Status changed to complete
16 Dec 2021, 17:07 GMT - Official notice release published
16 Dec 2021, 17:07 GMT - Buyer information updated
16 Dec 2021, 17:07 GMT
Lots and requirements (1)
Published by the contracting authority
- Lot 1 · #1Individual lot title not publishedcancelledPublished valueNot publishedIn order to assist with the tech transfer from Catapult the following items are being purchased are to be purchased asap: 1 x Sartorius Biowelder 1 x Sartorius Biosealer 1 x Sartorius BIOSTAT® RM 20 / 50 (BIOSTAT® B - perfusion ready) 1 x Sartorius Twin UniVessel 2 L STR + BIOSTAT® B Between 2022 and 2027 the following items may be purchased:- 2 x Sartorius Biowelder 2 x Sartorius Biosealer 2 x Sartorius BIOSTAT® RM 20 / 50 (BIOSTAT® B - perfusion ready) 2 x Sartorius Twin UniVessel 2 L STR + BIOSTAT® B 3 x Sartorius Biostat STR 50 3 x Sartorius kSep The above equipment will be used to furnish one research and development lab and two clean rooms. Installation, commissioning, consumables, training and annual support/maintenance/calibration will be incorporated for between 3 and 5 years as part of the purchase. Additional information: Regulation 32 of PCR 2015 is being applied as in 32. (2) (b) (ii) and 32. (5) (a). No contract will be entered into until after a 10 calendar day period from the submission of the VEAT notice date. As of 27/07/2022 The University of Sheffield has placed orders for the following equipment:- a) 1 x Sartorius Biowelder and 1 x Sartorius Biosealer b) 1 x Sartorius BIOSTAT® RM 20 / 50 (BIOSTAT® B - perfusion ready) and 1 x Sartorius Twin UniVessel 2 L STR + BIOSTAT® B c) 1 x Sartorius Biostat STR 50Contract periodNot publishedEligibilityNot publishedOptions / renewalNot published
Timeline
- Procedure published
27 Jul 2022, 11:15 BST - Award active
Not published · Not published - Award active
Not published · Not published - Award active
Not published · Not published - Contract active
Signed 14 Jul 2022, 00:00 BST · £226,000 - Contract active
Signed 11 Jul 2022, 00:00 BST · £228,000 - Contract active
Signed 31 May 2022, 00:00 BST · £58,000
Commercial outcome and competition
Awards SARTORIUS STEDIM UK LIMITED Not published · Not published · active SARTORIUS STEDIM UK LIMITED Not published · Not published · active SARTORIUS STEDIM UK LIMITED Not published · Not published · active |
Contracts Biostat RM 20/50L and Twin Univessel 2 L £226,000 · signed 14 Jul 2022, 00:00 BST · active Biostat STR 50L £228,000 · signed 11 Jul 2022, 00:00 BST · active Sartorius Biosealer and Bioweler £58,000 · signed 31 May 2022, 00:00 BST · active |
Bid statistics bids: 1 (lot 1) bids: 1 (lot 1) bids: 1 (lot 1) |
Buyer and organisations in this procedure
UNIVERSITY OF SHEFFIELD
Contracting authority GB-UKPRN-UKPRN 10007157Documents (0)
Official links; attachments are not copied
No linked documents are published
Related procedures (0)
No related procedures published
Planning and rationale
Planning budgetNot published |
No-engagement rationaleNot published |
Procedure rationaleThe University of Sheffield signed an agreement with Cell and Gene Therapy Catapult (CGT Catapult) to tech transfer the Catapult AAV (Adeno-Associated Virus) manufacturing platform to Gene Therapy Innovation Manufacturing Centre' (GTIMC). This task is one of the milestones under the funding award supporting the establishment of the GTIMC in Sheffield. The milestone must be completed within 12 months of the start of the GTIMC Project, i.e. by end July 2022. Any delay in the tech transfer will also impact on the milestone related to MHRA accreditation of GTIMX due by end Q4 2024.
Using exactly the same equipment as the set up at Cell and Gene Therapy Catapult facilities will minimise delays and reduce time/avoid the need for optimisation of manufacturing protocols at GTIMC and allow us timely and within budget achievement of tech transfer milestones, optimisation using non generic equipment may introduce inconsistent results and invalidate the process which as a result would delay process, characterisation and final production processes.
The GTIMC and University of Sheffield will jointly acquire a technology license from CGT Catapult to be able to use their AAV manufacturing platform. This platform was established and optimised based on the processes developed using the proposed list of equipment.
The list of equipment (as set out herein) and the estimated timescales we plan to purchase was included in our proposal to the MRC/LifeArc to secure funding for the establishment of GTIMC in Sheffield. The subsequent Grant Offer includes the specific brands/models of equipment set out herein.
A single source is therefore proposed to formalise the solution provided by Sartorius Stedim UK Limited for the following reasons: -
This equipment has been identified and is currently used by CGT Catapult and therefore to not use the same equipment would invalidate the Tech Transfer processes and agreements.
Furthermore, this specific equipment and supplier was identified by CGT Catapult as the optimum type to produce the results and treatments for the better advancement of the process, deviation from this would require significant lengthy additional optimisation which would significantly delay the process and miss funding milestones and therefore minimise delays and reduce time/avoid the need for optimisation of manufacturing protocols at GTIMC and allow us timely and within budget achievement of tech transfer milestones, optimisation using different equipment may introduce inconsistent results and invalidate the process which as a result would delay process, characterisation and final production processes.
Finally, the equipment set out herein will purely for the purpose of research, experiment, study or development within the University and no commercial licence will be held during the lifespan of this equipment. The prime functions of the GTIMC hub is to accelerate translational of gene therapy programs and clinical trials for rare monogenic diseases.
To increase the U.K. capacity for GMP clinical vector manufacturing using the catapult process to allow for expansion of U.K. skills and training within the GTIMC space and increase partnerships with other academia which will create a fertile ecosystem for innovation and research excellence in this field across academia. |