Additional Analytical Methods for NDNS Biomonitoring

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        "description": "Chemical Contaminants (Lot 2)\nChemical contaminants in food are unintentional and undesirable substances that may pose health risks at certain levels. Some examples of chemical contaminants include mycotoxins, heavy metals (such as lead and mercury), and organic pollutants (like dioxins). Chemical contaminants can enter the food chain from multiple sources, during primary or secondary production. Because of their potential impact on health, regulatory controls exist to limit consumer exposure, and it is essential to manage and reduce their presence in food.",
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        "description": "Analysis of biomarkers able to inform on exposure to the heavy metals, arsenic, cadmium, and lead. If it is technically feasible and cost effective, analysis of other metals that may be relevant to food safety may be proposed in the response to tender, in 400 NDNS Bioresource urine samples. \nMeasurement of urinary creatinine concentration to account for urine dilution and to enable estimation of exposure.\nDemonstration of an approach to estimating dietary intake of relevant metals from measured concentration of biomarker",
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    "title": "Additional Analytical Methods for NDNS Biomonitoring",
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    "description": "Tenders are invited to undertake a research project to identify suitable biomarkers of priority (groups of) additives (Lot 1) and contaminants (Lot 2), Metals (Lot 3) and develop and validate analytical chemistry methods for their quantitative measurement in human urine. In addition, an approach for estimating systemic exposure and theoretical dietary intake of each chemical of interest, from measured urinary excretion of the biomarker(s), should be derived.\nThe FSA is requesting that methods and approaches are determined, and proven for feasibility, for substances from the following food additive and other chemical contaminant groups, below or up to the estimated budget of £100,000 (exc. VAT) Lot 1 and £50,000 (exc VAT) each for lot 2 and 3. The substance groups have been prioritised in accordance with the FSA’s food safety remit and specific priorities. \nAll documents and communication for FSA funded projects must be submitted through the health-family single e-Commercial System (Atamis), using the following link: https://health-family.force.com/s/Welcome",
    "riskDetails": "Risks associated with a scientific services project of this nature may include (but not limited to) delays in project delivery, budgetary pressures, changes in scope or requirements, difficulties in obtaining representative samples, sampling plan amendments, sample quality or availability issues, laboratory capacity constraints, analytical method development and validation challenges, equipment failure, data quality concerns, regulatory or legislative changes, stakeholder availability, and delays in the provision of information, materials or approvals. There is also a risk that research findings or analytical results may not generate the expected outcomes, requiring additional investigation, testing, or revisions to the proposed approach. Suppliers will be expected to identify, manage and mitigate such risks throughout the contract lifecycle to ensure delivery of the agreed objectives, timelines and outputs.",
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  "date": "2026-06-02T18:56:44+01:00",
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    "title": "Additional Analytical Methods for NDNS Biomonitoring",
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    "description": "Premarket engagement for Additional Analytical Methods for NDNS Biomonitoring. \nThe Food Standards Agency (FSA) is seeking early market input to inform a potential future procurement relating to the development of analytical methods to support biomonitoring of food additives and chemical contaminants.\nThis work forms part of the FSA Chemical Hazards Programme and aims to improve understanding of UK consumer exposure through novel biomonitoring approaches.\nThe information gathered will be used solely to shape the FSA’s understanding of the market and to refine a potential future competitive procurement. Participation is voluntary, and non-participation will not disadvantage suppliers in any subsequent procurement process.\nAll documents and communication for FSA funded projects must be submitted through the health-family single e-Commercial System (Atamis), using the following link: https://health-family.force.com/s/Welcome",
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        "description": "The Food Standards Agency (FSA) is undertaking pre-market engagement to inform a potential future procurement for the development and validation of analytical methods to support biomonitoring of food additives and chemical contaminants.\nThis engagement seeks to:\nTest the feasibility of identifying and quantifying suitable urinary biomarkers for priority additive and contaminant groups\nUnderstand market capability and capacity to deliver analytical method development and validation within the proposed timeframes and budget\nGather insight into available methodologies (e.g. LC-MS, GC-MS, ICP-MS) and approaches to biomarker identification, including limitations and innovation opportunities\nInform the future procurement strategy, including lot structure, specification design, achievable scope, and value for money considerations\nSuppliers are invited to provide feedback on the proposed scope, including:\nFeasibility of delivering the requirements within ~10 months per lot\nThe number and type of substances that could realistically be covered within the indicative budget\nApproaches to biomarker selection, ADME evaluation, and method validation\nAny risks, constraints, or dependencies that should be considered\nThe information gathered will be used solely to shape the FSA’s understanding of the market and to refine a potential future competitive procurement. Participation is voluntary, and non-participation will not disadvantage suppliers in any subsequent procurement process.\nAll documents and communication for FSA funded projects must be submitted through the health-family single e-Commercial System (Atamis), using the following link: https://health-family.force.com/s/Welcome"
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