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Published 29 Jun 2022, 15:11 BST

Official UK procurement notice

Supply of a Biophysical Equipment System

Official notice

Authority: University of Dundee (Education)

GoodsOpen procedure
Sectors: Laboratory, optical and precision equipments (excl. glasses) (38) Delivery: Scotland (UKM71)
Budget not disclosedValue not published
Submissions closed 29 Jul 2022
Notice summaryFrom the published notice

Biophysical characterization of binary and ternary complex formations in proximity-inducing compounds is a key step in the iterative improvement of potency of Proteolysis Targeting Chimeras (PROTACs) and molecular glues. In order for us to have the ability to scrutinise the affinity and kinetics of binary and ternary complexes with challenging sample requirements (e.g. low affinity (1-10 uM) complexes, low protein availability, homoPROTACs etc) highly specialised systems are required.

What is being bought

Published requirement description

Biophysical characterization of binary and ternary complex formations in proximity-inducing compounds is a key step in the iterative improvement of potency of Proteolysis Targeting Chimeras (PROTACs) and molecular glues. In order for us to have the ability to scrutinise the affinity and kinetics of binary and ternary complexes with challenging sample requirements (e.g. low affinity (1-10 uM) complexes, low protein availability, homoPROTACs etc) highly specialised systems are required. The technique will provide a readout of compound/PROTAC affinity while providing insight into additional biophysical parameters, all of which can be critical for compound optimization/prioritization. This tender aims to substantially increase the ability of biophysicists and chemists to assess PROTAC/molecular glue biophysics and will be complimentary to techniques currently available to the new Center for Targeted Protein Degradation (CeTPD) (including SPR, ITC, TR-FRET) while being able to probe interactions that other techniques cannot currently scrutinise. The new machine will be housed in the CeTPD.

CPV: Laboratory, optical and precision equipments (excl. glasses)

The lotProcurement structure

single lot · no lot value published
Lot #1Renewal
Delivery: Scotland
Extensions: Extended warranty/service if taken out later and not at time of equipment purchase.Variant bids: not allowed
38000000 Laboratory, optical and precision equipments (excl. glasses)

What it takes to win
i

How this buyer will score bids.

The evaluation criteria and weights exactly as published on the notice, grouped by family (price, quality, social value and so on).

Evaluation split and conditions of participation as published; the tender pack may add more
Conditions of participation1
  • Suitability

    As detailed in SPD Scotland.

Procedure terms & legal framework

From the official record · publisher note attached
Procedure method
Open procedure
Legal basis
CELEX · 32014L0024 Public Contracts Regulations 2015 (Directive 2014/24/EU)
Procurement category
Goods
Notice status
Closed
Procurement threshold
Unspecified in notice
Regulatory regime
Standard
Commercial structure
Stand-alone contract (no framework)
Competition type
Competitive procedure
GPA / WTO covered
Yes (GPA)
Recurring procurement
No (one-off requirement)
First published
29 Jun 2022, 15:11 BST
Last source update
29 Jun 2022, 15:11 BST
Award evaluation window
29 Jul 2022 – …
Authority reference
UoD-LAB424-TC-2022
FTS notice number
2022/S 000-017780
Classification (CPV)
Laboratory, optical and precision equipments (excl. glasses)
Delivery area
Scotland (UKM71)
Official registry OCID
ocds-h6vhtk-034c1a Find a Tender
Contract terms
Electronic trading
e-invoicing allowed · electronic ordering · electronic payment
Performance terms

As detailed in the procurement documents.

Publisher note: NOTE: To register your interest in this notice and obtain any additional information please visit the Public Contracts Scotland Web Site at https://www.publiccontractsscotland.gov.uk/Search/Search_Switch.aspx?ID=698752. The buyer has indicated that it will accept electronic responses to this notice via the Postbox facility. A user guide is available at https://www.publiccontractsscotland.gov.uk/sitehelp/help_guides.aspx. Suppliers are advised to allow adequate time for uploading documents and to dispatch the electronic response well in advance of the closing time to avoid any last minute problems. (SC Ref:698752) Download the ESPD document here: https://www.publiccontractsscotland.gov.uk/ESPD/ESPD_Download.aspx?id=698752

How it was run

Official notice
Run through: Public Contracts Scotland · Who buys & how to bid on PCS
Supplier login requiredLanguage: EN
Access & registration note: Free single registration for Scotland; PCS-Tender (Jaggaer) for full bidding
Submission deadline
29 Jul 2022, 12:00 BST
Submission channel
{"electronicSubmission"}
Accepted languages
en
Bids opened
29 Jul 2022, 12:00 BST
Detailed submission instructions & authority contactsFrom official release

www.publiccontractsscotland.gov.uk ↗

Timeline

29 Jun 2022 → 29 Jul 2022 · 3 dates
  1. Notice published
    29 Jun 2022, 15:11 BST
  2. Submission deadline
    29 Jul 2022, 12:00 BST
  3. Bids opened
    29 Jul 2022, 12:00 BST

Contracting authority & participating public bodies

University of Dundee

Contracting authorityEducationBody governed by public lawEducation 4 King Edward Street, Markinch, Scotland, DD1 4HNContact name, email, phone Published organisation website ↗

Dispute resolution & review bodies

  • Dundee Sheriff CourtMediation bodyReview contact point DundeeContact phone

Official documents & specifications (2)

Official links; attachments are not copied

Tender pack and attachments

  • Economic and financial selection criteriatenderEconomic and financial selection criteria
  • Technical selection criteriatenderTechnical selection criteria